The donor materials based on ladder-type building blocks have been widely used in high-efficiency organic solar cells. With further study of nonfullerene acceptors for organic solar cells, researchers found that the ladder-type units show potential application and the recent power conversion efficiency for polymer solar cells is increasing very fast. The Research Group for Organic Functional Materials has made great efforts in design of novel ladder-type dipyran materials. They utilized the incorporated-O in the conjugated backbones to effectively elevate the electron donating ability for the D moiety and widened absorption behaviors. Then, a novel O-functionalized ladder-type dipyran building block (DTDP) is designed, which is the combination of the DTP and DBP segments and based on which two IC end-capped small molecule acceptors are designed. After the preliminary optimization, the acceptor based on DTDP demonstrated excellent photovoltaic performances (PCE = 9.40%). The corresponding research studies have been consecutively published on Nano Energy 2018, 45, 10-20 (SCI Q1, IF = 12.343).